Constipation is common.
What does the research show?
So, what is PEG 3350 anyway?
What is the FDA approved use of PEG?
How do we know it works?
How long can PEG be used in children?
What is the new study looking at?The FDA is looking at the safety of other molecules in the PEG 3350. PEG 3350 is a very large molecule that ins't absorbed by the gut, but there are concerns that smaller compounds could be found as impurities in the manufacturing process of PEG 3350 or formed when PEG 3350 is broken down within the body. The FDA is investigating if these smaller compounds are absorbed by the gut and accumulated in the bodies of children taking PEG 3350. Some families have reported concerns to the FDA that some neurologic or behavioral symptoms in children may be related to taking PEG 3350. It is unclear whether these side-effects are due to PEG 3350. This study is the first step towards trying to determine if there is truly a link.
If my child is on PEG 3350, should I stop?I cannot stress enough that the studies are not completed yet, so it is much too soon to say if there will be a link or not. I have years of experience with many children, and I have not seen any neurologic or behavioral problems caused by PEG 3350. It is important to note that many children with neurologic or behavioral problems are more likely to become constipated, so are more likely to need a medical treatment for constipation. This is an issue that pre-dates the medicine, so it is not caused by the medicine. Generally if the stools are softer, you can more easily work with the behavioral issues causing the constipation, such as loss of appetite/poor diet and failure to sit on the toilet long enough to empty the stool from the rectum. If you decide it is time to stop the medicine, be sure to discuss this with your child's doctor to keep them in the loop about how things are going!
Note: Originally published 1/26/15 and edited 2/19/17 to fix broken image link.